I'm worried about the side effects. Carbimazole is used for hyperthyroidism and other conditions. I was diagnosed with hyperthyroidism at Easter and am seeing the endocrinologist tomorrow. Secondly, if the carbimozole is slowly (and it can be a slow process) bringing your hormones under control and you are not experiencing any adverse reactions to the drug - you should try and stay with it. It happens to many. The rest of the time it’s a veggie diet. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. If abnormal liver function is discovered, the treatment should be stopped. The most important things are your thyroid levels, and you should have FT3 and FT4 measured every six weeks or so. If you don't have Graves disease there is a good chance of permanent remission of hyperthyroidism after 9-18 months. On 40mg, usual procedure is slow reduction down to 5mg, takes 18-24 months. Please dont think that removal of thyroid gland will magically make you feel better - you really will be exchanging one health condition for another as you will almost definitely become hypothyroid which brings its own problems (and you will not be able to go back from that point). i started taking carbimazole for my... View answer I’ve also started increasing my activity, which I can now do as I’m not exhausted all the time. I have just started on gluten free in the hope that when I come off Carbizamole I can manage through lifestyle - diet and exercise. Unfortunately my weight went from a 12 1/2S to 16st once I started the tablets. Rate Carbimazole to receive MedCheck, Discover best treatments based on user reviews of side effects, efficacy, health benefits, uses, safety and medical advice. Though less serious than other side effects, contact your doctor if any of these side effects become more bothersome or regularly occur. See below for a comprehensive list of adverse effects. I'm 51 and work in the media. The first was about 6 years ago and I was put on 25mg of Carbimazole a day. In effect - a walking wreck! Once diagnosed - I was on carbimozole and propranolol plus various treatments for the eye disease. I would think that the serious side effects of carbimazole are like most drugs, quite rare. Once Carbi becomes a problem then you have very few options. Carbi is a pill and a non extreme way to control Graves. The last thing on earth I would do is mess with my carbimazole dose though. A couple of things have occurred to me as I follow this thread. I had Graves in 2008 and unfortunately I developed the worst allergic reactions to Carbi and ended up in a hospital for some days under full-time observation... the worst experience ever (that is another story). I was on steroids and could do a thing because my heart was literally exhausted. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T 3 and T 4 Medical uses. Carbimazole is associated with an increased risk of congenital malformations, especially when administered in the first trimester of pregnancy and at high doses. If besides the weight gain you are feeling well under Carbi, keep it going and feel the luck. Carbimazole is a drug rightly used for treatment of hyperthyroidism. Ive been hypo for many years but on levothyroxine for two and am still gaining weight even thought i make sure I get daily exercise. Dose adjustments should be made in 2.5 mg increments. Removal or iodine treatment should always be absolute last resort when all else has failed. At the time of diagnosis my thyroid was out of control. Post your blood test results for all to see and comment on. The doctor placed me on 20mg of carbimazole a day. If Carbi is working for you, controlling your hormones level, you are one of the lucky ones! will i gain weight from the medication and what will happen if i stop taking?" Hello - I was diagnosed with Graves in 2015. I felt that this was a simpler solution for them but definitely not for me - as I’m the one who would be left with a life long condition that would then require medication for the rest of my life. I was told to watch out for a fever and sore throat, something to do with white blood cells. Thyroidectomy or radioactive ablatement will make you hypothyroid and should be a last resort if remission fails and you can't restart Carbimazole. Weight gain could cause … He told me the next steps were to take Carbizamole for the next 18 months. pregnancy, upcoming surgery, etc. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Carbimazole inhibits thyroxine so if you have too much of it, I guess it could make you feel like your thyroid is underactive, which would explain the exhaustion you're feeling. I am starting to consider to stop taking the medication as I really can't face it & just feel like I am replacing one health problem with another. A couple years have met a woman whose sister died from Carbi allergy (in Denmark). As my metabolism slowed down, my appetite has been slower to follow ! We know from studies such as this, that it is NOT uncommon for patients to gain around 5kg or 12 pounds when they start Methimazole (5). I read that you go back to your pre Graves weight. Carbimazole may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. Firstly, I notice that you refer to endos as ‘they’ - does this mean you are seeing a different endo each time you have your regular endo appointment at the hospital?This was an issue for me and after 18 months of it and with total frustration (every time I went the different endo tried to change my treatment and between them they ended up impeding my recovery) I asked my Gp to write and ask that I see only one (which I named) for all my future appointments. Mostly of muscle tissue, which is why your thigh muscles become weak. I have more energy, no palpitations, temperature controlled, hair grown back etc etc. Have they checked for antibodies it will tell you if you have graves or hashimios. There were also quite a few months when I really wasn’t up toop much exercise, and it’s been difficult to get back into the habit. Learn vocabulary, terms, and more with flashcards, games, and other study tools. ), allergies, pre-existing diseases, and current health conditions (e.g. Carbimazole is used for Hyperthyroidism etc. The starting dose of Felimazole Coated Tablets is 2.5 mg administered every 12 hours. Symptoms were heart palpitations, hair loss, brain fog, painful joints (esp. used to control an overactive thyroid gland (hyperthyroidism I went totally gluten free a couple of years ago and have totally reduced my thyroid antibody levels. Carbimazole - Indications, Dosage, Side Effects and Precautions General Brands Prescription Contraindications Side effects Dosage How to Take Warning Storage Medindia Common side effects which have been reported by users of Carbimazole include dizziness, drowsiness, headache, pain in the joints, nausea, vomiting, upset stomach, muscle pain, taste changes and numbness. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for CARBIMAZOLE. "i am taking 10mg of carbimazole daily for my hyperthyroism condition. Please don't even think about RAI or surgery its only a quick route to life long meds and a feeling of will I ever feel better being hypo. Remember, those easy weight loss years are gone. My main symptoms went (shaking, palpitations, anxiety, and generally feeling rubbish). The mother could then be treated with carbimazole from the second trimester throughout the remainder of the pregnancy, reducing the time of exposure of mother and fetus to the potentially hepatotoxic effects of propylthiouracil. Help with weight gain/trouble losing from thyroid being out of whack. If the dose you are on has helped to control your thyroid hormone - please don’t play around with it. If you ask for a copy of your results tomorrow, and publish them together with your carbimazole dose, and where that has been left the same or reduced, we may be able to help you further. Just a thought. I’ve put on some weight, although as yet, not quite as much I lost. Hyperthyroidism causes weight loss!. I took the decision to stop them as I suffered from some of the side effects and my white blood cells were being affected. legs), chronic fatigue, shakiness, hot flushes, freezing cold, eye problems (later diagnosed as thyroid eye disease) etc etc. Good to hear that a gluten free diet has helped balance / maintain thyroid balance. This means they can get a bit worked up when it's well outside range. At 16st and climbing (5'5" female) I am terrified of putting on more weight when I know I should be focused on loosing it. You need to have your levels tested to see whether you are overmedicated. I think part of the problem is that while I was very hyper, I could eat anything and not put on weight. Has anyone experienced anything similar or have any advice? Anyway. I have felt almost back to normal on... Thyroid/Graves Disease earlier this year. Hi, I have been diagnosed with hyperthyroidism and graves last year and since then I have put 2 stone on in less than a year, wondered if anyone has had the same issues , I'm on carbimazole. Commonly reported side effects of carbamazepine include: ataxia, dizziness, drowsiness, nausea, and vomiting. How much carbi are you on, when were your last tests, and do you have the results ? Some side effects of methimazole may occur that usually do not need medical attention. Carbi can cause several reactions. Although the Carbizamole has made me generally feel a bit better already, I have put on a stone since first taking them. Other side effects include: If you get any of the following side effects, they normally go away while you keep taking your medicine. So essentially my choices were to deal with the weight gain, or start popping pills to manage the side effects … The most common adverse effects associated with carbimazole administration are gastrointestinal signs (Bucknell, 2000). Hypothyroidism causes weight gain in the majority of patients and many find Levothyroxine replacement for hypothyroidism causes extra weight gain and hair loss. I won’t bore you with the long bumpy road of dealing with endos who were at times down ‘right dangerous’ through ‘less than useless’ to ‘okay’, but finally I have my thyroid under control. Thank you, I will post my results when I've had them done tomorrow and see what people think, to be honest I thought everything was under control but the tsh level isn't right which does concern me a little and I can'tget my head around it at all. My hormones have now been under control for about 6 months and I have had to adjust to the fact that when I was hyper my body was burning calories at a falsely fast rate and so, now that it is slowed down I have to adjust to that. The dose has to be well monitored and this medicine can not be used as means for weight loss. GPs (rightly or not) tend to use TSH alone when monitoring people who are hypothyroid, which is their main exposure to thyroid disease. Any side-effects that do occur are likely to be mild and wear off after a week or so. Go out there and look for a GP or Endo you can talk to and present your worries. If you don't have Graves disease there is a good chance of permanent remission of hyperthyroidism after 9-18 months. i was diagnosed with HyperT around a month ago and at diagnosis had a T4 reading of 38.8. If you are slowly getting better results with carbimozole and have been fortunate not to develop Thyroid Eye Disease then you should continue with that. vitamins, herbal supplements, etc. how much weight will i gain on carbimazole ? About 8 weeks ago I found out I had an overactive thyroid and was immediately put on 20mg Carbizamole daily whilst I waited to receive an appointment with a specialist. The problem is, your best chance of beating Graves' is to become euthyroid (within range) and stay there. The first was about 6 years ago and I was put on 25mg of Carbimazole a day. Hi, Thank you your reply it sounds like we had very similar symptoms and you have experienced the same issues with endocrine, being either useless or just Ok, I'm pleased to hear that weight loss can be achieved but more importantly to stay a good healthy weight and eat a healthy diet makes me feel a bit more reassured, I'm just a little frustrated with endocrine as I seem to get different stories every time I see them, they have not really talked about my tsh levels but my gp is concerned as they are very low at 0.02 but I'm going to discuss this with endo tomorrow as have an appointment with them and hopefully I will get some answers from them, I don't understand how they can say I am stable on carbimazole if my tsh is clearly saying everything is not as it should be, Thank you so much for your help and advice. Commonly reported side effects of itraconazole include: nausea. They prescribed synthroid. See below for a comprehensive list of adverse effects. This might be the best choice for you in the long term, but I'm just wondering why you think Carbimazole may not be right for you ? If the side effects of treatment, including weight gain, are intolerable to you, your doctor can help you find a new treatment. You may have to starting taking some Levo. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. unexpected death of my husband last year. Feeling sick (nausea) Headache or feeling dizzy; Skin rashes; Itching; Stomach upset ; Painful joints; Hair thinning; Changes to your taste. Can someone tell me what are the side effects and will it cause weight gain? Its not the Carbimazole itself that makes you gain weight, it's the effect it has on your thyroid gland. Carbimazole :: Stopping Carbimazole - Started To Gain Weight May 21, 2009. You have a serious autoimmune disease now which include several life threatening complications such as elevated heart rate and palpitations. I have been taking 75mcgs of T3 only for two and a half years. However, I did gain 2.5 stone once I started carbimozole. These side effects may go away during treatment as your body adjusts to the medicine. Can I just not willingly have the surgery/IRT immediately and get it overand done with? If they are still a problem after 2 weeks, or you are worried, contact your doctor but continue to give carbimazole. I was hyper for a long time before I was finally so ill it was obvious what was wrong and by that time I had lost masses and masses of weight. While this can be treated relatively easily with levo, you're just as likely to find it difficult to lose weight while you're hypo, if not more so. Iodine treatment and total thyroid removal are not a solution and should be the last resort. Long story short, they took a blood test and I was no longer within normal limits. This is partly why I became exasperated with the endo dept at my hospital (Whittington - North London) as they kept tweaking and messing with my treatment - often only looking at half the picture whilst at the same time constantly saying they could whip out my thyroid, if I’d prefer. Weight gain has been reported as one of the possible side effects. Before using Carbimazole, inform your doctor about your current list of medications, over the counter products (e.g. Know Carbimazole uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate.com Keep gaining weight and can't shift it help. 18-24 months off carbizole then same again. Do you have any problems with your eyes? Hyperthyroidism can cause weight gain so stopping Carbimazole may not help anyway. But probably better than surgeons playing with you, Hi sorry to hear your gaining weight so fast , I understand its so depressing. The most common side effects are feeling sick, upset stomach, headache, joint pain, skin rash and itching. My son is hyper and painfully thin but put on weight on carbinizole but after a year has gone into remission and is ok now. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. As long as you have your thyroid there remains the possibility to either stabilise it or for your Graves to go into remission. If you have to have your thyroid removed or zapped with RAI, you are likely to be hypo for the rest of your life. Thank you for your advice, I spoke to a lady where I worked who said similar to what you have, she was extremely poorly on carbimazole and had to come off it and in the end had her thyroid out, I am starting to wonder if maybe this is the way forward I'm not too sure. Hi again. I now eat less than I did before but a much healthier diet. I don’t eat wasted calories such as processed food and instead eat loads of veggie and fruit. Other side-effects you need to know about. If you are putting weight on at that rate you are probably becoming underactive. I had thyrotoxicosis/Graves' disease twice and the dosage depending on others results to start with is 20mg carbimazole, with regular blood tests to see any changes and change dosage.you do have to stay on the tablet for at least a year to make sure the thyroid is working ok. Don't stop carbimazole unless you are put on another thyroid medication otherwise graves will come back. i curtail this weight gain and even loose weight? I am coming off the stuff as I'd rather be dead than fat and will tell him that. Sorry to hear you're struggling I don't remember any side effects at all but maybe your dosage is too high. Last week I finally saw the specialist who thinks I have Graves Disease (awaiting confirmation). Carbimazole is used to treat hyperthyroidism. I have been diagnosed with hyperthyroidism and was given Carbimazole as the long term medication. The other drug acted on me the same way as Carbi and I had no alternative but Radio Iodine or surgery. Type: Prescribing and Technical Information (Add filter) I went from a size 8/10 to 14/16 and I understand completely how demoralising this is. Other side effects include:vomiting. This study showed that among 42 patients with Graves' disease that the average weight gain was around 12 pounds after starting Methimazole. I know, believe me, how weight gain can effect your self image - but your long term internal health outweighs this. The half-life may be prolonged due to the liver disorder. My advice is please don’t use your carbimozole dose as a weight loss aid. I almost died, I had a weird sort of paralysis/shock. If the dose you are on has helped to control your thyroid hormone - please don’t play around with it. I don’t know though. You dont want to mess up with it. Remember you have a thyroid for a reason - with good consistent treatment, good diet, exercise and sleep you could stabilise it and get it to work for you not against you. Hyperthyroidism can cause weight gain so stopping Carbimazole may not help anyway. And welcome to the club. Carbimazole tablets should be used with caution in patients with mild-moderate hepatic insufficiency. Thyroidectomy or radioactive ablatement will make you hypothyroid and should be a last resort if remission fails and you can't restart Carbimazole. Living with a galloping metabolism isn't viable in the long term, for one thing, you could end up damaging your heart. its really making me depressed. If you react badly to Carbi, your next step is radio iodine treatment (one I did) to kill you thyroid or surgery to remove it... You don't want any of those... Trust me. As Iv had this unpleasant experience twice with the gps refusing to believe me when I say I have a thyroid problem and them saying your tsh is fine so everything must be ok I had to fight to get the hospital, yes I ended up there to do a t3 and t4, t4 came back dangerously high at 95 when our hospital range is 12-22, so you can imagine the state I was in so Iv now opted for surgery which I know means medication for life. Other side effects include: pruritus, speech disturbance, amblyopia, and xerostomia. On rare occasions carbimazole can cause problems with … I know, believe me, how weight gain can effect your self image - but your long term internal health outweighs this. Thank you very much! Other adverse effects that have been reported include excoriations of the head and neck, lymphadenopathy, pruritus, lymphocytosis, and leucopenia (Mooney et al, 1992). My GP had indicated that the Carbizamole was a temporary fix and that ultimately I would need either surgery or iodine radio therapy to permantley fix the problem. Thyroid hormones control metabolic rate and thus a decrease in thyroid hormones will imply a decrease in metabolic rate … But honestly I did feel better after a short while of starting medication. Unfortunately my weight went from a 12 1/2S to 16st once I started the tablets. Since taking a long hard look at my exercise and diet habits I’ve lost half a stone and continue to lose weight and I’m now down to a size 12. Start studying side effects. Been on PTU since June (Carbimazole had bad side effects... medication I was taking and I have been the same weight for the last 6 years. Carbimazole :: Weight Gain Apr 14, 2010. Iv just been diagnosed with Graves’ disease, I feel this may be as a result of a stressful... diagnosed with hyperthyroidism and graves last year and since then I have put 2 stone on in less... avoid: uncooked veg, fluoride, soy, goitrogens, and take supplements including B complex, zinc,... been on 125mg levothyroxine since the day of my surgery. If so, it may be Thyroid Eye Disease which is made worse by RAI. A lot of people on Carbi eventually start taking some Levo. I have today been diagnosed for the 2nd time with an overactive thyroid. I went back over active in January, this is the 4th time. Dont rush into anything, it may seem like a long road, but trust me it is worth researching all you can before allowing something to be done, which you later regret. Do you know what your B12, vitamin D, ferritin and folate levels are as well as your thyroid results and what are your antibodies like now? Make new blood tests and maybe your future includes adding Levo to your daily routine (besides Carbi). Other side effects of amiodarone are rarer and are preventable by the use of a qualified medical provider to prescribe and, in the case of intravenous injection, administer amiodarone.

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